Uruz is the letter U
Anglo-Saxon Rune Poem (from ragweedforge.com)
The aurochs is proud and has great horns;
it is a very savage beast and fights with its horns;a great ranger of the moors, it is a creature of mettle
Uruz means auroch, a type of wild cattle that used to roam Europe and Asia. It is not extinct, having been hunted or domesticated away. A viable comparison might be to bison or buffalo or oxen. The horns of the auroch were highly prized as trophies, because managing to defeat one and kill it to take it’s horns was a significant challenge, and often a test of manhood and strength.
Uruz reversed refers to weakness or inability or inaction in shaping things to your desire. Rather then actively engaging and using your strengths, there is passivity and laziness, or illness or damage that is hampering your ability to act. This is quite literal for myself today, as I have pulled some muscles from over exertion, and having to act carefully because of it.